Fig. 3: Epigenetic signature of EBV tethering sites.
From: Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
a Heatmap comparison of 4C (MutuI cell, DS/Cp-1 bait, MboI restriction site) with other ChIP-seq data, AT rich sequence and gene density (5 kb bin, 500 kb range). ChIP-seq scores were converted to log values. Red color corresponds to maximum score. White color corresponds to average score. b Average sequence enrichment for the indicated ChIP-seq proteins and AT rich sequence classified into 10 groups based on the 4C (MutuI) scores (top: red → bottom: blue). c Box plot quantitation of ChIP-seq intensity overlapping 4C peaks or non-4C peaks. Boxplots show center quartiles, midlines show medians and whiskers extend to the data points, which are no more than 1.5× the interquartile range from the box. Error bar represents the standard deviation and P-value were calculated by two-sided Mann–Whitney U test. d UCSC genome browser image showing the comparison of 4C with other ChIP-seq data along the indicated chromosome.
