Fig. 5: High-frequency EBV tethering at transcriptionally silent neuronal genes.
From: Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
a Common 4C peaks ranked by the width of each peak for MutuI (top panel) and Raji (bottom panel) cells. b Venn diagram showing co-occupancy of top 10% common 4C peaks between MutuI and Raji (Top10% 4C-MutuI/Raji). c Distribution of Top10% 4C-MutuI/Raji on the graph of average reads per 100 kb (x-axis) and the maximum read per 100 kb (y-axis) acquired from MutuI/DS/Cp-1/Csp6I/Bio1 (top panel) and Raji/DS/Cp-1/Csp6I/Bio1 (bottom panel). d Positions and associated genes for Top10% 4C-MutuI/Raji across chromosomes plotted using NCBI genome decoration page. e Enrichment of tissue specific genes positioned in Top10% 4C- MutuI/Raji sites. f, g UCSC genome browser image showing the comparison of 4C data for MutuI and Raji with EBNA1-/H3K9me3- ChIP-seq data for MutuI along the indicated chromosome regions containing genes NRXN1 (panel f), NAV3, and SYT1 (panel g) specifically expressed in brain.
