Fig. 7: Histological analysis on osteogenesis and osseointegration at 8 weeks. | Nature Communications

Fig. 7: Histological analysis on osteogenesis and osseointegration at 8 weeks.

From: Alloying design of biodegradable zinc as promising bone implants for load-bearing applications

Fig. 7: Histological analysis on osteogenesis and osseointegration at 8 weeks.

a Van Gieson staining of representative cross sections in metaphysis, the magnified region is marked by red rectangle. NB, new bone; DP, degradation products; FT, fibrous tissue. Scale bar, 0.5 mm in low magnification, 500 μm in high magnification. b New bone area surrounding the implants, *P < 0.05, compared with Zn (n = 4, independent samples). c Bone-implant contact ratio, *P < 0.05, compared with Zn (n = 4, independent samples). d Zinc ion concentration in blood serum at 8 weeks, *P < 0.05, compared with control (n = 4, independent samples). *P < 0.05 by one-way ANOVA with Tukey’s post hoc test. For box-whisker plots, box edges correspond to 25th and 75th percentiles, lines inside the box correspond to 50th percentiles, and whiskers include minimum and maximum of all data points. Source data are provided as a Source Data file.

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