Table 1 Baseline characteristics of the n-3 LCPUFA and Vitamin D randomized controlled trials.

From: Prenatal dietary supplements influence the infant airway microbiota in a randomized factorial clinical trial

Category

Variable

Overall (n (%))

n-3 LCPUFA (n (%))

Placebo (n (%))

Vitamin D (n (%))

Placebo (n (%))

 

n

693

344

349

294

286

Socioeconomics (maternal)

Age; mean (sd)

32.29 (4.36)

32.33 (4.27)

32.24 (4.46)

32.50 (4.33)

32.01 (4.32)

 

Level of education:

     
 

 Low

55 (7.9)

25 (7.3)

30 (8.6)

20 (6.8)

25 (8.7)

 

 Medium

446 (64.4)

221 (64.2)

225 (64.5)

185 (62.9)

189 (66.1)

 

 High

192 (27.7)

98 (28.5)

94 (26.9)

89 (30.3)

72 (25.2)

 

Income level:

     
 

 Low

67 (9.7)

33 (9.6)

34 (9.7)

27 (9.2)

27 (9.4)

 

 Medium

366 (52.9)

178 (51.9)

188 (53.9)

151 (51.4)

153 (53.5)

 

 High

259 (37.4)

132 (38.5)

127 (36.4)

116 (39.5)

106 (37.1)

During pregnancy

 Smoking

54 (7.8)

21 (6.1)

33 (9.5)

20 (6.8)

26 (9.1)

 

 Cat or dog in home

234 (34.1)

117 (34.4)

117 (33.8)

88 (30.3)

105 (37.0)

 

 Antibiotic use

253 (36.6)

128 (37.3)

125 (35.8)

102 (34.8)

103 (36.0)

Child

 Sex (male)

354 (51.1)

168 (48.8)

186 (53.3)

154 (52.4)

144 (50.3)

 

 Race (caucasian)

664 (95.8)

332 (96.5)

332 (95.1)

282 (95.9)

274 (95.8)

 

Season of birth:

     
 

 Winter

212 (30.6)

98 (28.5)

114 (32.7)

107 (36.4)

102 (35.7)

 

 Spring

185 (26.7)

94 (27.3)

91 (26.1)

53 (18.0)

53 (18.5)

 

 Summer

148 (21.4)

74 (21.5)

74 (21.2)

62 (21.1)

57 (19.9)

 

 Fall

148 (21.4)

78 (22.7)

70 (20.1)

72 (24.5)

74 (25.9)

 

 Duration of breastfeeding

245 (155)

249 (159)

240 (156)

243 (145)

247 (165)

Birth

 Preterm delivery

27 (3.9)

12 (3.5)

15 (4.3)

10 (3.4)

9 (3.1)

 

 Nulliparity

318 (45.9)

153 (44.5)

165 (47.3)

121 (41.2)

140 (49.0)

 

 Antibiotics to mother

221 (32.0)

111 (32.4)

110 (31.7)

97 (33.2)

87 (30.5)

 

 Antibiotics to child

18 (2.6)

10 (2.9)

8 (2.3)

5 (1.7)

9 (3.2)

 

 Hospitalized

77 (11.1)

39 (11.3)

38 (10.9)

27 (9.2)

27 (9.5)

 

Delivery mode:

     
 

 Acute CS

84 (12.1)

47 (13.7)

37 (10.6)

39 (13.3)

33 (11.5)

 

 Vaginal

544 (78.5)

266 (77.3)

278 (79.7)

225 (76.5)

226 (79.0)

 

 Planned CS

65 (9.4)

31 (9.0)

34 (9.7)

30 (10.2)

27 (9.4)

  1. Percentages or standard deviations in parenthesis. No significant allocation differences were observed (chi-sq or t-test, p < 0.05)