Fig. 2: Scope of alkyl zinc reagent for nickel-catalyzed allylic carbonylative Negishi reaction.
From: Nickel-catalyzed allylic carbonylative coupling of alkyl zinc reagents with tert-butyl isocyanide
Reaction conditions: 1a (0.2 mmol), 2 (0.3 mmol), 3 (0.3 mmol), NiCl2·DME (0.02 mmol), DMA (2 mL), 25 °C, 0.5 h, and then 1 M HCl. aNi(cod)2 (0.02 mmol), 50 °C.
