Fig. 1: Describing the modular architecture of OGDs. | Nature Communications

Fig. 1: Describing the modular architecture of OGDs.

From: Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors

Fig. 1

a The molecular architecture of OGDs comprises a hydrophilic head, a hydrophobic tail, and a connecting linker. b, c OGD regioisomer mixtures based on first-generation [G1] or second-generation [G2] triglycerol are composed of different head group regioisomers (top), linker, and tail structures (bottom). The modular OGD architecture allows this detergent family to be optimized for protein purification, charge reduction, and lipid co-purification.

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