Table 1 Optimizations for cobalt-catalyzed hydroamination of styrene.

From: Ligand-promoted cobalt-catalyzed radical hydroamination of alkenes

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  1. aThe reaction was conducted using 1a (0.36 mmol), 2a (0.3 mmol), [Co] (5 mol %), ligand (6 mol%), PhSiH3 (0.36 mmol), and THF (1.2 mL) under N2 at r.t. for 12 h
  2. bDetermined by 1H NMR using TMSPh as an internal standard