Fig. 3: Model trained on adult hippocampus predicts location of samples from prenatal hippocampus. | Nature Communications

Fig. 3: Model trained on adult hippocampus predicts location of samples from prenatal hippocampus.

From: A molecular gradient along the longitudinal axis of the human hippocampus informs large-scale behavioral systems

Fig. 3: Model trained on adult hippocampus predicts location of samples from prenatal hippocampus.

The pattern of gene expression used to predict the location of adult hippocampus samples along the longitudinal axis were applied to samples extracted from the prenatal human hippocampus. Boxplots compare this normalized pattern of expression between samples extracted from the rostral and caudal hippocampus. Statistics are calculated using t-tests. ROC curves were generated using logistic regression. The top figures correspond to models fit using all features, whereas the bottom figures correspond to models fit using the smaller gene sets. ACC Accuracy. AUC Area Under the Curve. For boxplots, the center line, boxes and whiskers represent the median, inner quartiles, and rest of the data distribution (except outliers), respectively.

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