Fig. 6: Conservation of GFAT-1. | Nature Communications

Fig. 6: Conservation of GFAT-1.

From: Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis

Fig. 6

a Overview of conservation in GFAT-1 monomer A. The protein is presented as a cartoon and colored according to the ConSurf color scheme from variable to conserved residues (teal to bordeaux). Glc6P (yellow sticks), l-Glu (violet sticks), and UDP-GlcNAc (white sticks) are highlighted. b Protein sequence alignment of the interdomain linker of GFAT-1. Group 1 represents eukaryotes and group 2 prokaryotes. Red boxes indicate identical residues; red letters indicate similar residues. Source data are provided as a Source Data file.

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