Fig. 3: Rad52 droplet fusion can be promoted by flow-generating short nuclear microtubules. | Nature Communications

Fig. 3: Rad52 droplet fusion can be promoted by flow-generating short nuclear microtubules.

From: DNA repair by Rad52 liquid droplets

Fig. 3

a, b pti-DIM extension/shortening (a, white arrowhead) correlates with Rad52 droplet velocity (a, b). c–f CFD-based modelling of pti-DIM motion shows that it can generate flow that drives Rad52 droplet fusion when pti-DIM velocity is applied at ~90° (d) but not at 110° (e) relative to the axis connecting the centre of the droplets. Fusion is driven by an inter-droplet decrease in pressure that is shown in gradients (d, e) and quantifications (f). Scale bar, 1 µm.

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