Table 1 Catalytic parameters for hNAA50, hNatE, and hNatE/HYPK.

From: Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK

 

kcat (min−1)

Km (μM)

kcat/Km (μM−1 min−1)

hNAA50*

3.45

831.5

4.15 × 10−3

hNatE*

3.09

96.2

3.21 × 10−2

hNatE/HYPK

0.81

73.1

1.11 × 10−2

  1. *Calculation of kinetic parameters for hNAA50 and hNatE is based on an independent replicate of experiments previously reported46. Source data are provided in the Source Data file.