Fig. 1: IP subunits expression is associated with better prognosis. | Nature Communications

Fig. 1: IP subunits expression is associated with better prognosis.

From: Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma

Fig. 1

a, b Kaplan–Meier plot of TCGA melanoma patients (n = 472), where the survival of patients with high (a) IP expression, and (b) Mutational load (top tertile; blue) is compared with that of the patients with the low counterparts (bottom tertile; yellow) (logrank P = 0.00014 and P = 0.27 with median survival time difference 4094 and 783 days, respectively). c The estimated abundance of CD4 + T-cell, CD8+ T-cell, regulatory T-cell (Treg), NK cell (NK), M1 macrophage (M1), and cytolytic score (CYT score) of patients with high IP subunits expression (top tertile; blue) are higher compared to patients with low IP subunits expression (bottom tertile; yellow) (FDR-corrected Wilcoxon ranksum P < 0.05).

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