Fig. 4: Summary of the effects of mutations induced by the activity of APOBEC3.
From: Mutations in the HPV16 genome induced by APOBEC3 are associated with viral clearance
Viral APOBEC3-induced mutations are illustrated in the circle plot by viral gene region in the inner ring for low variant allele fraction (VAF) somatic mutations in red, and the outer ring for high VAF constitutive variants in blue for all individuals in the PaP cohort (mutations in both cases and controls are illustrated). Modified from the Cancer Genome Atlas Research Network35.
