Table 2 Summary of the cohort of MDS/AML families.
From: The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants
Characteristics | Number of families (%) |
|---|---|
Clinical phenotype | |
MDS | 12 (14) |
AML | 17 (19.8) |
MDS/AML | 18 (20.9) |
MDS/AML/TCP | 15 (17.4) |
MDS/AML/BMF | 24 (27.9) |
Family history of hematological disease | 86 (100) |
Consanguinity | 3 (3.5) |
Other malignancies/disorders | |
Non-hematological cancers | 12 (14) |
Neurological disorders | 7 (8.1) |
Other hematological malignancies (CML, ALL, non-Hodgkin’s lymphoma) | 3 (3.5) |
Pulmonary fibrosis | 2 (2.3) |
Liver disease | 2 (2.3) |
