Table 1 Parameters of the native inducible systems.

From: A genome-wide approach for identification and characterisation of metabolite-inducible systems

Inducible system

Inducer

Dynamic range, in -folda

Kmb

hc

OapR/PH16_RS01330

β-Alanine

8.0 ± 0.4

201 ± 24 µM

0.75 ± 0.05

FdsR/PH16_RS03165

Formate

4.5 ± 0.2

130 ± 7 µM

1.05 ± 0.04

XdhR/PH16_RS05055

Xanthine

16.0 ± 1.0

13.0 ± 1.4 µM

1.03 ± 0.10

PhgR/PH16_RS05530

Phenylglyoxylate

144.8 ± 106.5

595 ± 133 µM

0.96 ± 0.13

NahR/PH16_RS08125

Salicylate

650.8 ± 317.4

2.12 ± 0.49 µM

0.66 ± 0.08

BenM/PH16_RS09790

Benzoate

74.1 ± 10.7

12.6 ± 0.8 µM

1.64 ± 0.14

TtdR/PH16_RS10665

Tartrate

370.6 ± 232.2

61.5 ± 22.9 mM

0.80 ± 0.09

SauR/PH16_RS13695

Sulfonatoacetate

395.4 ± 193.7

7.3 ± 4.9 mM

0.57 ± 0.06

KynR/PH16_RS14030

L-kynurenine

26.9 ± 2.1

2.64 ± 0.18 µM

0.98 ± 0.05

HpdR/PH16_RS18295

3-Hydroxypropanoate

25.2 ± 1.7

13.2 ± 1.9 µM

0.64 ± 0.03

PhhR/PH16_RS18365

L-phenylalanine

9.0 ± 0.8

16.9 ± 2.2 µM

0.59 ± 0.04

GabR/PH16_RS23655

GABA

ND

ND

ND

HpdA/PH16_RS24175

L-tyrosine

38.3 ± 5.0

9.9 ± 2.2 µM

0.72 ± 0.07

BadR/PH16_RS27200

Cyclohexanecarboxylate

11.4 ± 10.9

43.8 ± 13.0 µM

1.11 ± 0.28

PcaQ/PH16_RS30145

3,4-Dihydroxybenzoate

77.2 ± 29.8

8.63 ± 0.40 µM

0.98 ± 0.03

AcoR/PH16_RS19445

Acetoin

11.1 ± 1.6

1.23 ± 0.07 µM

1.36 ± 0.10

  1. Data are mean ± SD, n = 3. Source data are provided as a Source Data file. ND - not determined.
  2. aDynamic range is defined as the -fold increase in fluorescence calculated by dividing the maximum level of fluorescence output by the basal level of fluorescence output.
  3. bKm represents the inducer concentration at which the half-maximal activation of the inducible system is achieved.
  4. ch—Hill coefficient.