Table 2 The impact of pretreatment TRL on the diagnostic performance of 18F-FDG-PET/CT during LN staging in gynecological cancer patients (primary cohort).

From: Pretreatment tumor-related leukocytosis misleads positron emission tomography-computed tomography during lymph node staging in gynecological malignancies

  

Cervical cancer (n = 127)

Endometrial cancer (n = 203)

Ovarian caner (n = 96)

  

False-positive PET/CT results

False-positive PET/CT results

False-positive PET/CT results

 

Yes (n = 10)

No (n = 117)

P-value

Yes (n = 12)

No (n = 191)

P-value

Yes (n = 8)

No (n = 88)

P-value

WBC count (/μL)

<9000

4 (3.6)

106 (96.4)

<0.0001

5 (2.7)

181 (97.3)

<0.0001

3 (3.6)

81 (96.4)

<0.0001

 

≥9000

6 (35.3)

11 (64.7)

 

7 (41.2)

10 (58.8)

 

5 (41.7)

7 (58.3)

 
  1. Statistical significance was assessed using two-sided Fisher’s exact test.
  2. FDG fluorodeoxyglucose, PET positron emission tomography, CT computed tomography, WBC white blood cell.