Table 3 Univariate/multivariate analyses for false-positive 18F-FDG-PET/CT results.

From: Pretreatment tumor-related leukocytosis misleads positron emission tomography-computed tomography during lymph node staging in gynecological malignancies

  

Univariate analysis

Multivariate analysis

Variables

Odds ratio

95%CI

P-value

Odds ratio

95%CI

P-value

Cervical cancer

Age (years)

<50

1

  

1

  

≥51

1.39

0.38–5.06

0.6193

2.52

0.55–12.96

0.2324

FIGO stage

IA-IIA

1

  

1

  

IIB

0.41

0.05–3.38

0.4067

0.20

0.01–1.79

0.1637

Histology

SCC

1

  

1

  

Others

0.66

0.18–2.44

0.5291

0.62

0.12–2.87

0.5439

Tumor size (mm)

<40

1

  

1

  

≥40

2.22

0.54–8.36

0.2554

1.84

0.30–9.80

0.4875

WBC count (/μL)

<9000

1

  

1

  

≥9000

14.45

3.53–59.16

0.0002

15.39

3.48–79.23

0.0004

Endometrial cancer

Age (years)

<50

1

  

1

  

≥51

0.45

0.13–1.57

0.2107

0.59

0.10–3.41

0.5563

FIGO stage

IA-IIB

1

  

1

  

IIIA-IVB

2.84

0.87–9.32

0.0842

2.31

0.41–13.24

0.3451

Histology

EAC

1

  

1

  

Others

2.48

0.71–8.75

0.1565

4.11

0.80–21.10

0.0904

Peritoneal cytologya

Negative

1

  

1

  

Positive

1.34

0.34–5.30

0.6722

0.98

0.15–6.55

0.9831

WBC count (/μL)

<9000

1

  

1

  

≥9000

25.34

6.82–94.14

<0.0001

31.03

6.57–146.53

<0.0001

Ovarian cancer

 

Age (years)

<50

1

  

1

  

≥51

4.00

0.47–33.99

0.2042

5.62

0.42–75.29

0.1919

FIGO stage

IA-IIB

1

  

1

  

IIIA-IVB

1.84

0.43–7.86

0.4114

3.28

0.37–28.91

0.2839

Histology

SAC

1

  

1

  

Others

1.00

0.19–5.32

1.0000

3.27

0.31–34.05

0.3209

Peritoneal cytologya

Negative

1

  

1

  

Positive

1.79

0.40–7.94

0.4462

1.92

0.29–12.83

0.5010

WBC count (/μL)

<9000

1

  

1

  

≥9000

19.29

3.79–98.07

0.0004

31.72

4.45–225.98

0.0006

  1. Statistical significance was assessed using multiple logistic regression analysis.
  2. FDG fluorodeoxyglucose, PET positron emission tomography, CT computed tomography, FIGO International Federation of Gynecology and Obstetrics, SCC squamous cell carcinoma,
  3. EAC endometrioid adenocarcinoma, SAC serous adenocarcinoma, WBC white blood cell.
  4. aPeritoneal cytology was not indicated for 4 cases in endometrial cancer and 1 case in ovarian cancer.
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