Fig. 5: Predicting students’ gut microbiotas in the next 3 months using a dynamic Bayesian network model.
From: Environmental remodeling of human gut microbiota and antibiotic resistome in livestock farms
DbRDA of the Bray–Curtis PCoA of the unweighted UniFrac distances between the gut microbiota in samples at the seven time points tested and three predicted future time points. Display is based on sample scores on the primary constrained axis (CAP1, 2.2% variance explained) and primary multidimensional scaling (MDS1, 20% variance explained). Lines connect samples taken at the same time point, and colored circles indicate the samples near the center of gravity for each time point. Below and left boxplots show the sample scores in CAP1 and MDS1 (boxes show medians/quartiles; error bars extend to the most extreme values within 1.5 interquartile ranges). Coding: 0, baseline; 1–3, during the swine farm stay; 4–6, 3 months after leaving the farm; 7–9, predicted time points over 3 months in the future (n = 14 biologically independent samples per timepoint for 0–6 and n = 14 predicted points per timepoint for 7–9). *P < 0.05; **P < 0.01; ***P < 0.001; NS, not significant; Student’s t-test (paired two-sided test between the students’ samples at time point T0 versus time points T3, T6, T7, T8, and T9). Underlying data are provided in the Source Data file.
