Fig. 3: Grp expression is enriched in a subset of sensory neurons with both peptidergic and non-peptidergic markers. | Nature Communications

Fig. 3: Grp expression is enriched in a subset of sensory neurons with both peptidergic and non-peptidergic markers.

From: Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors

Fig. 3: Grp expression is enriched in a subset of sensory neurons with both peptidergic and non-peptidergic markers.

a, c, e IHC image of tdTomato with CGRP (a), IB4 (c), and TRPV1 (e) in GrptdTom DRG. Arrowheads indicate double stained neurons. Scale bar, 50 μm. b, d, f Venn Diagram of DRG neurons with tdTomato/CGRP expression, tdTomato/IB4-binding, and tdTomato/TRPV1 expression from GrptdTom mice. g ISH of Grp and Mrgpra3 in WT DRG. Scale bar, 20 μm. h Diagram of DRG neurons with Grp and Mrgpra3 expression. i ISH of Grp and Hrh1 in WT DRG. j Diagram of DRG neurons with Grp and Hrh1 expression. n = 3 mice and 9 sections.

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