Fig. 5: The biosensing application of CONFINED-based biosensor. | Nature Communications

Fig. 5: The biosensing application of CONFINED-based biosensor.

From: Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids

Fig. 5

a Fluorescence confocal imaging of HeLa cells incubated with Czyme-in-2 without and with l-histidine, respectively. The scale bars are 20 μm. b The relative fluorescence intensity of Czyme-in-2 confocal imaging that quantified by ImageJ; Data are presented as mean values ± s.d. (n = 3), Student’s t test, ***p = 0.00043 < 0.001, by two-tailed unpaired Student’s t-test. c Schematic illustration of ATP aptamer encapsulated in the DNA cages (Cage-apt-in-2). d Fluorescence response in the presence of different concentrations of ATP, ranging from 0 to 10 mM. Inset: relationship between fluorescence enhancement and concentrations, data are presented as mean values ± s.d. (n = 3). Source data are provided as a Source Data file.

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