Fig. 6: The in vivo pharmacokinetic, imaging, and biodistribution studies of the THPG vesicles. | Nature Communications

Fig. 6: The in vivo pharmacokinetic, imaging, and biodistribution studies of the THPG vesicles.

From: In situ supramolecular polymerization-enhanced self-assembly of polymer vesicles for highly efficient photothermal therapy

Fig. 6: The in vivo pharmacokinetic, imaging, and biodistribution studies of the THPG vesicles.The alternative text for this image may have been generated using AI.

a Blood clearance curve as a function of time after tail intravenous injection of THPG vesicles in rat (n = 3 biologically independent rat) (ID stands for injected dosage). b In vivo fluorescence images of MCF-7 tumor bearing mice with different times after intravenous injection of THPG-Cy7.5 vesicles and Cy 7.5, respectively (Ex: 745 nm, Em: 820 nm; mode: fluorescence). White arrows were used to indicate tumors location. c Ex vivo images of isolated organs and tumors at 24 h post-injection of THPG-Cy7.5 vesicles and Cy 7.5, respectively. d Biodistribution of THPGs at 1, 4, and 24 h post-injection. (n = 3 biologically independent mice). Data are presented as mean values +/− S.D., and P values are calculated by two-tailed Student’s t-test *P < 0.05, **P < 0.005.

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