Fig. 3: Increased heat production in HFD-fed ASK1Δadipo mice.
From: ASK1 inhibits browning of white adipose tissue in obesity
a Light (day) and dark (night) oxygen consumption in HFD-fed ASK1F/F (n = 8) and ASK1Δadipo (n = 11) mice during a 24-h period at RT. **p = 0.020 (light), **p = 0.010 (dark). b Light (day) and dark (night) oxygen consumption in HFD-fed ASK1F/F (n = 7) and ASK1Δadipo (n = 6) mice during a 24-h period after 20 days housing at thermoneutrality. #p = 0.073, *p = 0.042. c Light (day) and dark (night) heat production in HFD-fed ASK1F/F (n = 8) and ASK1Δadipo (n = 11) mice during a 24-h period at RT. **p = 0.009. d Rectal temperature measured in HFD-fed ASK1F/F (n = 7) and ASK1Δadipo (n = 7) mice. *p = 0.015. Values are expressed as mean ± SEM. Statistical tests used: two-sided t-tests for (a–d). Source data are provided as a Source Data file.
