Fig. 2: Functional responses of projecting and non-projecting neurons are indistinguishable.
From: Impact of visual callosal pathway is dependent upon ipsilateral thalamus
a Coronal rat brain section showing the CTB-Alexa 594 injection site and retrogradely labeled neurons in contralateral V1 (upper) expanded view of retrogradely labeled projection neurons location across cortical layers (lower left, from upper image). Lower right: Overview of neurons labeled with OGB-1 (green, e.g. neuron 2) with callosal projecting neurons (VCPNs) co-labeled with CTB (red, e.g. neuron 1). b Fraction of VCPNs as a function of depth from the pia (N = 3 animals). c Pooled data of spontaneous (gray) and maximum stimulus response (black, average max. response to preferred orientation for VCPNs (N = 28 neurons) and non-VCPNs (N = 33 neurons)) and mean ± SD (red) for each group. d Distribution of preferred orientations for orientation selective neurons from both VCPN and non-VCPN groups (ipsi-eye stimulation, red, contra, turquoise). e Scatter plot comparing mean stimulus response of ipsi- to the mean response from the contralateral eye stimulation (lower) for VCPNs (orange markers) and non-VCPNs (blue markers) with the distribution of the contralateral bias index shown in upper panels (see “Methods” section for details).
