Fig. 1: Overview of WGS analysis. | Nature Communications

Fig. 1: Overview of WGS analysis.

From: Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia

Fig. 1

WGS data were generated using identical protocols at the same facility and all WGS data were jointly processed and analyzed. The schizophrenia cases also had GWA SNP array and exome-sequencing data for comparison for the purpose of quality assessment. We started with 1165 schizophrenia cases and 942 ancestry-matched population controls. After QC, 1162 cases and 936 controls remained. Variant annotation focused on empirically determined annotation methods.

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