Fig. 1: Transcriptome and proteome allocation are better correlated at the process level than the gene level.
From: Nitrogen limitation reveals large reserves in metabolic and translational capacities of yeast
a Absolute mRNA and protein abundances were quantified in yeast chemostat cultures at a dilution rate D = 0.2 h−1. Mean values of biological duplicates for the carbon-limited condition are shown. See Supplementary Fig. 2D-F for other conditions. b Transcriptome and proteome allocations to 99 GO-slim processes under carbon-limited condition were calculated as a % (mol mol−1) of total transcripts and proteins. GO-slim processes are color-coded by functional category. The number of GO-slim terms curated in each functional category is shown. See Supplementary Data 2 for number of genes in each GO-slim term. c Enrichment of GO-slim terms in 200-gene sliding windows of relative transcript abundance was analyzed by Fisher’s exact test. Y-axis represents relative # of GO-slim terms belonging in each functional category with FDR-adjusted pFisher < 0.05. Numbers indicate the relative abundance of transcripts (% mol mol−1 of total transcripts) in the 200-gene window at the dashed lines. d As in c for proteome organization.
