Fig. 5: Ribosome reserves contain diverse sub-stoichiometric ribosomal proteins (RP).
From: Nitrogen limitation reveals large reserves in metabolic and translational capacities of yeast
a RP : rRNA ratio for each RP (abundance of each RP divided by rRNA abundance) was calculated in all growth conditions. The p-values indicated are from two-sided Student’s t-tests. Center line, median; box limits, upper and lower quartiles; whiskers, 1.5× interquartile range. b Model of ribosome complex diversity and abundance. Each complex ribosome contains 54 “core” RP subunits that are highly expressed and samples a subset of 22 RP subunits expressed an order of magnitude lower. c The total number of ribosomes in the cell decreases, whereas diversity of ribosomes varies quadratically, with the number of RP subunits complexed. d Relative abundance of RP subunits in N-limited chemostats compared with C-limited chemostat. RP paralogs were summed and labeled with standard gene name. The 17 RP subunits that were selectively upregulated by >2-fold in N-limited chemostats are indicated with a gray dot.
