Fig. 5: LEfSe analysis identified baseline vaginal microbiota biomarkers associated with clinical outcomes at 12 months follow-up.

a Cladogram representing taxa at all phylogenetic levels with significantly different abundance according to clinical outcome at 12-month follow-up. The size of the circle is proportional to the abundance of taxon represented. b Histogram of LDA scores found to differ significantly in abundance between those who regressed compared to those who did not regress. LDA linear discriminant analysis. Analysis restricted to top 20 taxa with all remaining taxa denoted as ‘other’.