Table 1 Patient characteristics of 87 patients included in study cohort.
Non-regression at 12 months, n = 45 | Regression at 12 months, n = 42 | All, n = 87 | p-value | |
|---|---|---|---|---|
Age, years | 0.1951 | |||
Mean (SD, range) | 20.1 (2.4, 16.0–24.9) | 20.8 (2.6, 16.1–26.5) | 20.5 (2.4, 16.0–26.5) | |
Ethnicity, n/N (%) | 0.6112 | |||
Caucasian | 17/45 (37.8) | 20/42 (47.6) | 37/87 (42.5) | |
Black | 8/45 (28.9) | 9/42 (21.4) | 17/87 (19.5) | |
Latin | 11/45 (24.4) | 8/42 (19.0) | 19/87 (21.9) | |
Other ethnicity | 9/45 (8.9) | 5/42 (11.9) | 14/87 (16.1) | |
Smoking, n/N (%) | 0.4808 | |||
Current smoker | 14/45 (31.3) | 10/42 (23.8) | 24/87 (27.6) | |
Non-smoker | 31/45 (68.9) | 32/42 (76.2) | 63/87 (72.4) | |
Weekly alcohol use, n/N (%) | 1.000 | |||
Yes | 1/45 (2.2) | 0/42 (0) | 1/87 (95.4) | |
No | 44/45 (97.8) | 42/42 (100.0) | 86/87 (4.6) | |
Weekly drug use, n/N (%) | 0.5415 | |||
Yes | 5/45 (11.1) | 7/42 (16.7) | 12/87 (13.8) | |
No | 40/45 (88.9) | 35/42 (83.3) | 75/87 (86.2) | |
Current/previous vaginal douching, n/N (%) | 0.6337 | |||
Yes | 13/45 (28.9) | 10/42 (23.8) | 23/87 (26.4) | |
No | 32/45 (71.1) | 32/42 (76.2) | 64/87 (73.6) | |
Contraception, n/N (%) | 0.6491 | |||
Nil | 14/45 (31.1) | 17/42 (40.5) | 31/87 (35.6) | |
Contraceptive injection | 8/45 (17.8) | 7/42 (16.7) | 15/87 (17.2) | |
Other oral combined hormonal contraception | 23/45 (51.1) | 18/42 (42.8) | 41/87 (47.2) | |
Previous pregnancy, n/N (%) | 0.6682 | |||
Yes | 22/45 (48.9) | 18/42 (42.9) | 40/87 (46.0) | |
No | 23/45 (51.1) | 24/42 (57.1) | 47/87 (54.0) | |
Number of sexual partners | 0.5136 | |||
Mean (SD, range) | 8 (8, 1–35) | 7 (6, 2–25) | 8 (7, 1–35) | |
Current sexual practice, n/N (%) | 0.0971 | |||
Abstinence | 32/45 (71.1) | 28/42 (66.7) | 60/87 (69.0) | |
Monogamous | 9/45 (20.0) | 4/42 (9.5) | 13/87 (15.0) | |
Non-monogamous | 4/45 (8.9) | 10/42 (23.8) | 14/87 (16.0) | |
History of anal intercourse, n/N (%) | 0.7674 | |||
Yes | 6/45 (13.3) | 7/42 (16.7) | 13/87 (15.0) | |
No | 39/45 (86.7) | 35/42 (83.3) | 74/87 (85.0) | |
History of genital infections, n/N (%) | 0.8195 | |||
Chlamydia trachomatis | 8/45 (17.8) | 14/42 (33.3) | 22/87 (25) | 0.1384 |
Neisseria gonorrhea | 1/45 (2.2) | 3/42 (7.1) | 4/87 (5) | 0.3493 |
Trichomonas vaginalis | 2/45 (4.4) | 1/42 (2.4) | 3/87 (3) | 1.000 |
Genital warts | 5/45 (11.1) | 5/42 (11.9) | 10/87 (11) | 1.000 |
Syphilis | 0/45 (0) | 0/42 (0) | 0/87 (0) | 1.000 |
Bacterial vaginosis | 5/45 (11.1) | 9/42 (21.4) | 14/87 (16) | 0.2475 |
Yeast infection | 21/45 (46.7) | 21/42 (50.0) | 42/87 (48) | 0.8313 |
HSV | 2/45 (4.4) | 3/42 (7.1) | 5/87 (6) | 0.6693 |
HIV | 0/45 (0) | 0/42 (0) | 0/87 (0) | 1.000 |
HPV status, n/N (%) | 1.000 | |||
Negative | 3/45 (6.7) | 3/42 (7.1) | 6/87 (6.9) | |
Positive | 40/45 (88.9) | 39/42 (92.9) | 79/87 (90.8) | |
High-risk HPV status | 0.4315 | |||
Positive | 38/40 (95.0) | 35/39 (89.7) | 73/79 (92.4) | |
Negative | 2/40 (5.0) | 4/39 (10.6) | 14/79 (7.6) | |
HPV16 status | 0.4826 | |||
Positive | 14/38 (36.8) | 16/35 (45.7) | 30/73 (41.1) | |
Negative | 24/38 (63.2) | 19/35 (54.3) | 43/73 (58.9) | |
HPV18 status | 0.7125 | |||
Positive | 5/38 (13.2) | 3/35 (8.6) | 8/73 (11.0) | |
Negative | 33/38 (86.8) | 32/35 (91.4) | 65/73 (89.0) | |
Low-risk HPV status | 0.4978 | |||
Positive | 15/40 (37.5) | 18/39 (46.2) | 33/79 (41.7) | |
Negative | 25/40 (62.5) | 21/39 (53.8) | 46/79 (58.3) | |
Number of HPV subtypes | 0.4823 | |||
Single | 16/40 (40.0) | 12/39 (30.8) | 28/79 (35.4) | |
Two or more | 24/40 (60.0) | 27/39 (69.2) | 51/79 (64.6) | |
Unknown | 2/45 (4.4) | 0/42 (0) | 2/87 (2.3) |
