Table 1 Flight indices of Drosophila expressing varying amounts of transgenic versus endogenous Act88F.

From: A role for actin flexibility in thin filament-mediated contractile regulation and myopathy

Genotype

Tg:Endo

Flight index

n

Act88FWT/+

1:1

5.05 ± 0.08

206

Act88FM305L/+

1:1

3.85 ± 0.11#

212

Act88FWT/Act88FWT;+

2:1

3.98 ± 0.11

199

Act88FM305L/Act88FM305L;+

2:1

1.74 ± 0.08#

227

Act88FWT/Act88FWT

2:0

0.00 ± 0.00

222

Act88FM305L/Act88FM305L

2:0

0.00 ± 0.00

222

  1. Tg:Endo refers to the ratio of transgenic to endogenous Act88F gene copy numbers. Data are presented as mean ± SEM. #Significantly different from the corresponding WT control line as determined by the Mann–Whitney test (P ≤ 0.0001). Source data are provided as a Source Data file.