Fig. 4: EE2-induced liver injuries, bile acid dysregulation, and PTB in pregnant mice.
From: Dysregulation of bile acids increases the risk for preterm birth in pregnant women
a The gestation days, PTB rates, and rates of live birth in controls (n = 9) and EE2-treated pregnant mice (n = 12). The data are presented as mean ± SD in the right and left panels. b The sTBA levels in controls (n = 9) and EE2-treated mice (n = 12) and a negative correlation between sTBA concentrations and the gestation days or the rates of live birth. The means and standard errors of the group values were indicated by the long and short lines, respectively. Student’s t test for pairwise comparison (two-sided), Chi-squared test for proportion comparisons, and Pearson correlation analysis were applied for statistical analysis. Source data are provided as a Source Data file.
