Fig. 5: CCl4-induced liver injuries, bile acid dysregulation, and PTB in pregnant mice.
From: Dysregulation of bile acids increases the risk for preterm birth in pregnant women
a The gestation days, PTB rates and rates of live birth in controls (n = 9) and pregnant mice treated with 1.0 (n = 5), 1.5 (n = 9), or 2 ml kg−1 CCl4 (n = 5). b The sTBA levels in controls (n = 9) and mice treated with 1.5 kg ml−1 CCl4 (n = 9) and a negative correlation between sTBA concentrations and gestation days or the rates of live birth. The means and standard errors of the group values were indicated by the long and short lines, respectively. Student’s t test for pairwise comparison, one-way ANOVA followed by Tukey post hoc test for multiple group comparison, Chi-squared test for proportion comparisons and Pearson correlation test were applied for statistical analysis. Source data are provided as a Source Data file.
