Fig. 7: Elevated bile acids, not liver injury, induced PTB.
From: Dysregulation of bile acids increases the risk for preterm birth in pregnant women

a The gestation days and PTB rates in control (n = 9) and mice treated with a combination of 0.3% CA and DY268 (n = 8). b The sTBA concentrations in the control (n = 9) and treatment group (n = 8). c The AST levels in control (n = 9) and mice treated with a combination of CA and DY268 (n = 8). d Representative hepatic histopathology of control and mice treated with CA and DY267. Consistent results were obtained from the control (n = 8) and treated mice (n = 8). Student’s t test for pairwise comparison (two-sided) and Chi-squared test for proportion comparisons were applied for statistical analysis. Source data are provided as a Source Data file.