Fig. 3: CRP was negatively associated with prefrontal-limbic TSPO availability and positively associated with PTSD severity. | Nature Communications

Fig. 3: CRP was negatively associated with prefrontal-limbic TSPO availability and positively associated with PTSD severity.

From: PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies

Fig. 3

a Lower [11C]PBR28 VT was significantly associated with higher levels of CRP (R2 = 0.52, p = 0.005; β = −0.92, p = 0.029) in the PTSD group (n = 21). Displayed [11C]PBR28 VT values are adjusted for genotype and sex. b Higher CRP was significantly associated with greater PTSD severity (R2 = 0.21, p = 0.037) in the PTSD group (n = 21). Coefficient of determination and standardized coefficients were assessed using linear regression. Gray shading indicates 95% confidence intervals.

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