Table 1 Participant characteristics and injection parameters.

From: PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies

Characteristics

Control (n = 26)

PTSD (n = 23)

p-value

Age: years

32 ± 12

38 ± 10

0.10

Sex

8 F, 18 M

10 F, 13 M

0.36

Body mass index

27.3 ± 4.3

27.8 ± 5.4

0.68

rs6971 Genotype

17 HAB, 9 MAB

18 HAB, 5 MAB

0.32

Ethnicity (%)

  

0.32

  African American

6 (23)

9 (39)

 

  Asian/Pacific Islander

1 (4)

1 (4)

 

  Caucasian

12 (46)

9 (39)

 

  Hispanic

7 (27)

4 (17)

 

Clinical Characteristics

PTSD severity

   

  CAPS-IV (n)

—

71 ± 24 (10)

—

  CAPS-5 (n)

—

32 ± 10 (13)

—

Trauma exposure(s)

(n = 16)

  

  Sexual trauma

3

12

—

  Physical trauma

10

21

—

  Childhood trauma

11

23

—

  Combat

3

9

—

  Accident/natural disaster

13

17

—

Years since primary trauma (n)

16 ± 10 (12)

16 ± 11 (22)

0.91

Current comorbid MDD

—

18

—

Currently on psychotropic medication

—

5

—

Current tobacco users

12

8

0.41

Current cannabis users

4

7

0.21

Current alcohol users

17

13

0.53

Injection parameters

 Injected dose (MBq)

502.6 ± 189.3

573.9 ± 165.7

0.17

 Injected mass (µg/kg)*

0.03 ± 0.03

0.01 ± 0.01

0.022

 fP

0.024 ± 0.008

0.020 ± 0.007

0.14

  1. *significant at p < 0.05; assessed from two-sided independent samples t-test.
  2. Values are Mean ± SD, unless otherwise specified.