Table 3 Concentrations (nM) of endogenous brain oxytocin (OT).

From: Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques

 

80 IN

40 IN

80 IV

Monkey ID # (Sex)

ID #2 (M)

ID #4 (M)

ID #1 (F)

ID #5 (F)

ID #3 (F)

ID #6 (F)

Cerebellum

ND

<1

12

<1

ND

+

Brainstem

28

19

40

51

60

20

Striatum

9

97

3

7

79

86

Amygdala

32

131

NM

214

25

40

Thalamus

6

17

24

40

21

155

Visual Cortex

ND

ND

ND

ND

ND

ND

Insular Cortex

ND

<1

NM

2

1

ND

dPFC

ND

1

ND

1

2

ND

mPFC

ND

<1

<1

<1

ND

ND

OFC

2.2

9

1

5

2

ND

Hypothalamus

368

3200

895

Hippocampus

15

5

5

  1. ND not detected, NM not measured, + detected but not quantifiable, OT xytocin, dPFC dorsal prefrontal cortex, mPFC edial prefrontal cortex, OFC orbital frontal cortex, CSF cerebrospinal fluid, Mmale, F female, IN intranasal, IV intravenous.
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