Table 1 Table listing the somatic mutations detected for the tumor and LN metastasis.

From: Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas

Gene_Name

Samples with mutation

(COSMIC_ID)

Total mutations in gene

Protein coding changes

Is a kinase?

Is a GPCR?

ADRA1D

Metastasis, tumor

 

1

p.Arg282Cys

 

Yes

MAP2K2

Metastasis

 

1

p.Gln391His

Yes

 

ACCSL

Tumor

 

1

p.Pro382Ser

  

ALCAM

Metastasis, tumor

 

3

p.Arg304Lys(T/M),p.Arg304Ser(T/M),p.Ser324Pro(T/M)

  

ATP10A

Tumor

 

1

p.Met1280Thr

  

MUC3A

Tumor

 

1

p.Thr2064Asn

  

MYC

Tumor

 

1

p.Ser21Asn

  

OR2L8

Tumor

COSM226497

1

p.Leu132Pro

  

OR5R1

Metastasis, tumor

 

1

p.Leu101Gln

  

PLEKHA5

Metastasis, tumor

 

1

p.Gln412fs

  

PPP1CC

Tumor

 

2

p.Ile244Leu, p.Phe227Ser

  

RP1L1

Tumor

COSM3762979

1

p.Glu1343Lys

  

TG

Metastasis, tumor

 

1

p.Thr1432_Ser1433del

  

ZFP42

Metastasis, tumor

 

1

p.Lys231Asn

  
  1. Enlists protein-altering gene mutations detected in exome analysis of tumor and LN metastatic lesions from the patients.