Fig. 2: Visualization of single-cell data by FLOW-MAP. | Nature Communications

Fig. 2: Visualization of single-cell data by FLOW-MAP.

From: Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line

Fig. 2

Each dot represents an individual cell. The distance between each pair of cells represents the overall multi-omic dissimilarity between them. Cell pairs that are close enough are linked with an edge in between. The colors of the dots in the main panel (upper left) represent BRAFi exposure time (0, 1, 3, or 5 days) of the corresponding cells. Dot colors in the other panels represent the abundance of each marker in each cell. The dashed-line box in the panels for MITF, MART1, and Ki67 levels show a small subpopulation of day-0 cells that are slow-cycling with less melanocytic phenotype.

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