Fig. 4: Non-invasive MRI of BCSFB function: proof of application to the human brain at 3T.
From: Non-Invasive MRI of Blood–Cerebrospinal Fluid Barrier Function
a High resolution FLAIR structural images showing the location of CP tissue within the lateral ventricles. b Corresponding axial control ASL images at TE = 400 ms. c The mean ASL signal (normalised to the average ASL signal in CP containing ROIs) as a function of TI for CSF regions with (black line) and without (grey line) CP tissue. Each line represents an individual subject (n = 3 biological replicates on three healthy volunteers over three separate experiments).
