Fig. 1: Current model of GAG biosynthesis in A. fumigatus. | Nature Communications

Fig. 1: Current model of GAG biosynthesis in A. fumigatus.

From: Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation

Fig. 1

a Schematic of the five co-regulated genes of the GAG cluster found on chromosome 3. The location on the chromosome is is denoted by nucleotide (nt) number. b Cartoon representation of the GAG biosynthesis system based on bioinformatics and previous studies including the two crystal structures of the glycoside hydrolase domains of Sph3 (PDB 5C5G) and Ega3 (PDB 6OJ1). The synthesized polymer is hypothetical in sequence as the GAG polymer is heterogeneous.

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