Fig. 2: Agd3 is a multi-domain protein with a conserved electronegative cleft. | Nature Communications

Fig. 2: Agd3 is a multi-domain protein with a conserved electronegative cleft.

From: Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation

Fig. 2

a Linear representation of Agd3 domains based on the structure. b Agd3 in cartoon representation displaying the three-domain arrangement: the N-terminal α/β/α-fold in yellow; the catalytic CE-domain in pink; and the C-terminal β-rich domain in teal. Zinc ions are depicted as gray spheres. c Surface representation of amino acid conservation colored from variable (teal) to conserved (fuchsia) as calculated by Consurf85. d Electrostatics surface representation shows an electronegative cleft. Electrostatics were calculated by APBS in PyMol (v. 2.0.7) and visualized in blue to red (+10 kT/e to −10 kT/e)86.

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