Fig. 2: Substrate scope.

a Substrate scope of primary alcohols. b Substrate scope of secondary alcohols. c Substrate scope of the benzoylcyclopentenes. Reaction conditions: X = I, 1 (0.1 mmol), 2 (1 mmol), Pd₂dba₃•CHCl₃ (5 mol%), L1 (20 mol%), K₂CO₃ (0.2 mmol) in 1 mL solvent, 100 °C, 36 h, under CO (1 atm). Yields of isolated products are given. The dr values were determined by ¹H NMR analysis. The ee values were determined by HPLC analysis on a chiral stationary phase. ^aX = Br. ^b48 h.