Table 1 Mast cells and neutrophils enrichment in pancreas of nPOD donors.
From: Large-scale electron microscopy database for human type 1 diabetes
Group | CaseID | Pancreas Region | AAb (RIA) | Age (years) | Duration (years) | Mast cells total | Mast cells T+ | Neutrophils |
|---|---|---|---|---|---|---|---|---|
Non-diabetes | 6098a | Head | – | 18 | – | 4.5 | 0 | 0 |
6098b | 0 | 0 | 0 | |||||
6126a | 3.2 | 0 | 0 | |||||
6126b | Head | – | 25 | – | 0 | 0 | 0 | |
6126c | 3.5 | 0 | 0 | |||||
6130 | Head | – | 5 | – | 4.8 | 4.8 | 0 | |
6131 | Head | – | 24 | – | 0 | 0 | 0 | |
6153 | Head | – | 15 | – | 0 | 0 | 0 | |
6160 | Head | – | 22 | – | 1.0 | 1.0 | 1.0 | |
6227 | Head | – | 17 | – | 0 | 0 | 0 | |
6229 | Head | – | 31 | – | 0 | 0 | 0 | |
6230 | Body | – | 16 | – | 0 | 0 | 0 | |
6232 | Head | – | 14 | – | 0 | 0 | 0 | |
6233 | Head | – | 14 | – | 0 | 0 | 0 | |
6331 | Body | – | 27 | – | 0 | 0 | 0 | |
6374 | Head | – | 14 | 0 | 0 | 0 | ||
6412a | Head | – | 17 | – | 0 | 0 | 2.6 | |
6412b | 0 | 0 | 0 | |||||
6417a | Head | – | 18 | – | 0 | 0 | 0 | |
6417b | Body | 11.2 | 0 | 0 | ||||
Pregnancy | 6226 | Head | – | 38 | – | 2.3 | 0 | 0 |
Average | 1.4 ± 0.6 | 0.8 ± 0.6 | 0.2 ± 0.1 | |||||
AAb+ | 6151 | Head | GADA | 30 | – | 2.1 | 0 | 0 |
6156 | Head | GADA | 40 | – | 5.6 | 0 | 1.1 | |
6158a | Head | GADA, mIAA | 40 | – | 0 | 0 | 0 | |
6158b | 5.0 | 0 | 0.6 | |||||
6197 | Head | GADA, IA-2A | 22 | – | 0 | 0 | 0 | |
6301 | Body | GADA | 26 | – | 1.2 | 1.2 | 0 | |
6303 | Body | GADA | 22 | – | 1.7 | 1.7 | 0 | |
6314a | Head | GADA | 21 | – | 4.0 | 4.0 | 0 | |
6314b | Body | 0.6 | 0.6 | 0 | ||||
6388 | Body | GADA, mIAA | 25 | – | 0 | 0 | 3.5 | |
6397 | Body | GADA | 21 | – | 2.4 | 2.4 | 0 | |
6400 | Body | GADA | 25 | – | 3.3 | 3.3 | 0 | |
6421 | Body | GADA | 6 | 0 | 0 | 0 | ||
6424a | Head | GADA, mIAA | 17 | – | 7.8 | 7.8 | 0 | |
6424b | Body | 5.0 | 5.0 | 9.9 | ||||
6433a | Body | GADA | 23 | – | 2.4 | 2.4 | 0 | |
6433b | 0 | 0 | 0 | |||||
Average | 2.4 ± 0.6 | 1.7 ± 0.6 | 0.9 ± 0.6 | |||||
Type 1 Diabetes | 6063 | Head | – | 4 | 3 | 2.5 | 2.5 | 1.2 |
6064 | Head | GADA, IA-2A, ZnT8A | 20 | 9 | 1.2 | 1.2 | 39.1* | |
6087a | Head | ZnT8A | 18 | 4 | 6.7 | 6.7 | 0 | |
6087b | 5.9 | 5.9 | 0 | |||||
6113 | Head | – | 13 | 1.6 | 0 | 0 | 12.8 | |
6198a | Tail | GADA, IA-2A, ZnT8A | 22 | 3 | 5.6 | 5.6 | 8.4 | |
6198b | 4.1 | 4.1 | 24.6 | |||||
6204a | Body | GADA | 28 | 21 | 0 | 0 | 21.7 | |
6204b | 0.8 | 0 | 21.7 | |||||
6209 | Head | IA-2A, ZnT8A | 5 | 0.25 | 0 | 0 | 0 | |
6211a | Body | GADA, IA2A, ZnT8A | 24 | 4 | 0.9 | 0.9 | 0 | |
6211b | 1.2 | 0 | 0.6 | |||||
6228a | Head | 0 | 0 | 0 | ||||
6228b | GADA, IA-2A, ZnT8A | 13 | 0 | 0 | 0 | 9.8 | ||
6228c | Body | 0 | 0 | 0 | ||||
6243a | Body | – | 13 | 5 | 3.4 | 3.4 | 1.7 | |
6243b | 2.4 | 2.4 | 2.4 | |||||
6337 | Head | – | 20 | 5 | 4.5 | 4.5 | 0 | |
6360 | Body | – | 5 | 2.5 | 0 | 0 | 0 | |
6362 | Body | GADA | 25 | 0 | 3.3 | 3.3 | 0 | |
6380 | Body | – | 11 | 0 | 1.3 | 1.3 | 0 | |
6405 | Head | GADA, IA2A, ZnT8 | 29 | 0.6 | 7.5 | 7.5 | 0 | |
6436a | Body | IA2A | 26 | 3 | 0 | 0 | 0 | |
6436b | Head | 4.1 | 4.1 | 21.6* | ||||
Average | 2.3 ± 0.5 | 2.2 ± 0.5 | 6.9 ± 2.2 | |||||
Type 2 Diabetes | 6124 | Head | – | 62 | 3 | 0 | 0 | 0 |
6133 | Head | – | 46 | 20 | 1 | 0 | 3.8* | |
Average | 0.6 ± 0.6 | 0 | 1.9 ± 1.3 | |||||
