Fig. 2: Overall structure of the DmpRΔD-phenol complex.
From: Tetrameric architecture of an active phenol-bound form of the AAA+ transcriptional regulator DmpR
a Upper: domain organisation of the DmpRΔD protein. Lower: protomer structure of phenol- and zinc-bound DmpRΔD with side (left) and top-down (right) views. The putative position of the DNA-binding domain is indicated by a grey dotted circle. b Overall structure of the tetrameric DmpRΔD-phenol complex. Each protomer is individually represented, with the P1 (light blue)/P2 (wheat) dimer shown as cartoons and the P3 (pale yellow)/P4 (light pink) dimer shown as surface representations. c Structure of the P1/P2 head-to-head dimeric DmpRΔD–phenol complex. d The putative location of the DNA-binding domains within the tetrameric complex.
