Fig. 3: βPFOAβ(1-42) samples can be enriched in either tetramers or octamers. | Nature Communications

Fig. 3: βPFOAβ(1-42) samples can be enriched in either tetramers or octamers.

From: Aβ(1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage

Fig. 3

SEC of βPFOsAβ(1-42) prepared at low (a) and high (d) Aβ(1-42) concentration in a column equilibrated in DPC. The peaks labeled in orange and blue are assigned, respectively, to Aβ(1-42) tetramers and octamers. SDS-PAGE analysis of βPFOsAβ(1-42) prepared at low (b) and high (e) Aβ(1-42) concentrations either not cross-linked (ctrl) or having been previously cross-linked (XL) and showing the effect of boiling (+) and non-boiling (−). MALDI-TOF analysis of βPFOsAβ(1-42) prepared at low (c) and high (f) Aβ(1-42) concentrations. Data shown in panels b and e are representative from three independent experiments. Source data are provided as a Source data file.

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