Fig. 8: Type I IFN/IFNAR axis is a regulator of adipocyte-intrinsic inflammatory potential. | Nature Communications

Fig. 8: Type I IFN/IFNAR axis is a regulator of adipocyte-intrinsic inflammatory potential.

From: Type I interferon sensing unlocks dormant adipocyte inflammatory potential

Fig. 8: Type I IFN/IFNAR axis is a regulator of adipocyte-intrinsic inflammatory potential.

A proposed model of how type I IFN/IFNAR axis unlocks adipocyte inflammatory vigor, through modulation of adipocyte core metabolism. Adipocyte-specific IFNAR expression modifies the severity of obesity-associated glucose dysmetabolism in mice with limited impact on hepatocellular damage. Source data are provided as a Source data file.

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