Fig. 2: Enantioselective palladium-catalysed hydrosilylation of maleimides. | Nature Communications

Fig. 2: Enantioselective palladium-catalysed hydrosilylation of maleimides.

From: Stereospecific Si-C coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides

Fig. 2

a The determination of chiral palladium catalyst after screening of a variety of chiral ligands and reaction parameters, and that corresponding to L12 is optimal. b The catalytic asymmetric hydrosilylation of maleimides is broadly applicable, affording silyl products with excellent enantioselectivities (up to 99% ee). Products containing S-heterocycle and unsubstituted imide can be accessed. c The effect of bulky groups at the ortho-position of N-arylmaleimides on enantioselective Si–C coupling hydrosilylation with respect to the remote control of axial chirality.

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