Fig. 2: Predictive fiber tracts in training cohorts.
From: A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder
Top: all fibers connected to the sum of volumes of tissue activated (VTAs) of each cohort are shown in green. Middle: predictive fibers positively associated with clinical improvement are shown in red. Only positive fibers are shown here for reasons of clarity. See Fig. 3 for negatively associated tracts. The top 20% predictive fibers are displayed. Bottom: correlations between the degree of stimulating positively predictive tracts (sum of aggregated fiber T-scores under each VTA) and clinical improvements. Gray shaded areas represent 95% confidence intervals. This analysis is based on a normative connectome, a replication of it based on anatomically predefined pathways is shown in Supplementary Fig. 1.
