Fig. 10: Summary of ZIKV-induced metabolic reprogramming of human placenta and specialized hubs that contribute to ZIKV life cycle.
From: Metabolic reprogramming by Zika virus provokes inflammation in human placenta

By increasing placental lipid overload, ZIKV deprives the fetus of essential lipids and contributes to massive inflammation which may further impair the barrier function of the placenta.