Fig. 5: Spatial resolution of fUS responses.
From: Transfer functions linking neural calcium to single voxel functional ultrasound signal
a Quantification of fUS responses (area under the curve, ET 1%, 5 s) in the voxel containing the most sensitive glomerulus (outlined with a blue frame) and the five neighboring voxels (A–E, n = 5 mice, GL glomerular layer, EPL external plexiform layer). The color map shows that only in one case, the largest response was located in the blue voxel. The color bar was scaled with respect to the highest AUC value across the six voxels. b Statistical analysis (GLM) of fUS responses in the corresponding voxels using the RBC velocity response (CBV flowing at 0.5–1.5 mm s−1) as a regressor. The t value for the voxel containing the most sensitive glomerulus was not systematically the highest one. The applied statistical threshold was p < 0.01 + FWE correction. NS for not significant. c Quantification of fUS responses (AUC) for four stimulation conditions. For the five mice, the voxel containing the most sensitive glomerulus and the other five voxels were ranked with the 1st place assigned to the voxel with the highest AUC value. d Statistical quantification of fUS responses with ranking based on t values. The 1st place was assigned to the highest t value. Source data are provided as a Source Data file.
