Fig. 3: GO enrichment analysis for NTRK2 in GBM or LGG. | Nature Communications

Fig. 3: GO enrichment analysis for NTRK2 in GBM or LGG.

From: A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways

Fig. 3

a Schematic of DGCA analysis for the top 350 genes significantly positively correlated with NTRK2 in LGG or GBM. GO terms for biological processes in top 350 differentially expressed genes in GBM compared with normal brain (b) and GO terms for the top 350 differentially expressed genes in the cellular component in GBM compared with normal brain (c) revealed a predominance of genes implicated in morphogenesis and proliferation, as well endocytic compartments and vesicular transport. d Gene ontology enrichment terms for the genesets within the reactome pathways in top 350 differentially expressed genes in LGG compared with normal brain.

Back to article page